Starcast Join the waitlist
Return on Health

Return on Health

Everything You Know About Calories Is Wrong | Dr. Robert Lustig

Sep 6, 2026 · 1h 10m

Coming soon to iPhone. Already have it? “Listen in Starcast” takes you straight there.

About this episode

What if one of the most basic ideas in nutrition — that a calorie is a calorie — is the wrong way to think about metabolic health? For decades, Robert Lustig has argued that obesity, diabetes and other chronic metabolic diseases cannot be understood through energy balance alone. His central argument: what happens to food after we eat it matters, and added sugar — particularly fructose — can disrupt metabolic function in ways calorie counting fails to capture. In this episode of Return on Health, hosts Niko Hems and Miguel Medina challenge Robert on how strong that case actually is. They discuss his research on sugar restriction, controlled feeding trials that appear to contradict some of…