Isaac Mizrahi Talks Food, Culture; Says “I Don’t Really Feel Unzipped Changed my Life”

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The restoration and rerelease of Unzipped—the ur-fashion documentary— with Janus this September has had the Vogue office abuzz for months. Ahead of its run in theaters The Run-Through co-host Nicole Phelps—who says the film was her “gateway drug to fashion,” met with inimitably charming Isaac Mizrahi, designer, performer, the film’s star and since June 2026, Target’s first Creative Director at Large, to talk supermodels, and not mixing work with love—or Ambien. “It was a very good moment in fashion,” conjectures Mizrahi about the continuing draw of the film. “I bet if you had substituted some other fabulous, funny people in that movie, it would've been good. Mm. You know? It was just a good…