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The a16z Show

The a16z Show

From Vibe Coding to Vibe Researching: OpenAI’s Mark Chen and Jakub Pachocki

Sep 25, 2025 · 52m

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About this episode

What comes after vibe coding? Maybe vibe researching. OpenAI’s Chief Scientist, Jakub Pachocki, and Chief Research Officer, Mark Chen, join a16z general partners Anjney Midha and Sarah Wang to go deep on GPT-5—how they fused fast replies with long-horizon reasoning, how they measure progress once benchmarks saturate, and why reinforcement learning keeps surprising skeptics. They explore agentic systems (and their stability tradeoffs), coding models that change how software gets made, and the bigger bet: an automated researcher that can generate new ideas with real economic impact. Plus: how they prioritize compute, hire “cave-dweller” talent, protect fundamental research inside a product…