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The a16z Show

The a16z Show

Greg Brockman on Why OpenAI Says We’re Entering the AGI Era

Sep 14, 2026 · 51m

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Ben Horowitz and Erik Torenberg sit down with OpenAI co-founder and President Greg Brockman to discuss why he believes AI has entered a new phase, what OpenAI’s latest models reveal about the path to AGI, and the safety and security challenges that come with increasingly capable systems. Greg explains why computer use represents such an important step for agents, including models that can work coherently for 24 hours and interact with software through the same interfaces humans use. He also shares how OpenAI deployed 10,000 agents to tackle the Navier-Stokes problem, and why advances in mathematical reasoning could translate into new approaches to science, software, and cybersecurity. Ben,…