
Passion Struck with John R. Miles
Alzheimer’s Research, Doctored Data, and the Human Cost | Charles Piller – EP 722
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What happens when the systems we trust most struggle to correct themselves and the cost is paid by patients, families, and society?In this deeply consequential episode of Passion Struck, investigative journalist Charles Piller joins the show to discuss his groundbreaking book Doctored: Fraud, Arrogance, and Tragedy in the Quest to Cure Alzheimer’s. Piller, a senior writer for Science magazine, has spent years examining how Alzheimer’s research became shaped by incentives, reputation, and institutional inertia—and what that meant for scientific progress and human lives.At the center of this conversation is a pivotal 2006 Nature paper that helped cement the amyloid hypothesis as the dominant…