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The Inflammation Code

The Inflammation Code

Why Is Weight Loss So Hard in Midlife? Karen Martel on Hormones, HRT & Perimenopause

Jun 2, 2026 · 54m

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About this episode

If you've been eating well, exercising consistently, and still watching your body change in ways that don't make sense, this episode is for you.Karen Martel is a Certified Hormone Specialist, Certified Thyroid Specialist, and host of the globally ranked Hormone Solution Podcast. She went through early menopause at 42, rebuilt her health twice, and has spent the last decade helping women understand what's really happening during perimenopause, and what to do about it before symptoms steal years of their vitality.In this candid, science-forward conversation with Dr. Shivani Gupta, Karen breaks down the most common myths around HRT, explains why women are being undertreated, and makes a…