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Extend Podcast with Darshan Shah, MD

Extend Podcast with Darshan Shah, MD

117. Dr. Steven Gundry: The Microbiome War Shaping Your Mind

Dec 2, 2025 · 1h 11m

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About this episode

Most people think about the gut as a digestive system, yet emerging research shows it functions more like a command center shaping immunity, metabolism, mood, and even coronary artery calcification. The surprising twist is that your gut may be influencing your brain more than your brain influences your gut. In this episode of Extend, we sit down with Dr. Steven Gundry, cardiac surgeon and world leading expert on the microbiome, to uncover how gut bacteria communicate with your mitochondria and brain, why leaky gut silently drives inflammation throughout the entire body, and how keystone species like Akkermansia help rebuild the gut barrier. We break down the role of vitamin D in activating…