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Extend Podcast with Darshan Shah, MD

Extend Podcast with Darshan Shah, MD

63. Charles Brenner: NAD, Energy, and Longevity: The Secret Nobody Told You About

May 20, 2025 · 1h 12m

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About this episode

What if the reason you're tired, inflamed, or not recovering the way you used to has nothing to do with aging, and everything to do with your NAD system being under attack? In this episode of Extend, I'm joined by Dr. Charles Brenner, the scientist who discovered nicotinamide riboside (NR) and one of the leading experts on NAD metabolism. We unpack why NAD is so critical for energy, repair, and resilience, and why simply "taking NAD" isn't the solution most people think it is. We also break down the key lifestyle factors quietly draining your NAD levels, the real difference between NMN, NR, niacin, and IV NAD, and why NR may be the safest and most effective way to support your body's…