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A Bit of Optimism

A Bit of Optimism

Revisited: The Power of Saying "Screw It" with Rob Lowe

Sep 29, 2026 · 1h 2m

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About this episode

Hello from Team Simon! We're taking a few weeks off and will be back with brand-new episodes of A Bit of Optimism on Tuesday, October 27. Until then, we're revisiting some of our favorite conversations, starting with one of the most fun we've ever had: Rob Lowe. Maybe you know the feeling: you've got an idea, a joke, a risk you want to take… and you talk yourself out of it before anyone else gets the chance. Rob Lowe has spent four decades doing the opposite. He calls it a healthy case of the "screw-its." It's how he survived an industry famous for chewing people up. He went from movies to The West Wing when movie stars didn't do TV, and from TV to hosting a game show when that was supposed…