Starcast Join the waitlist

This Week in Virology

TWiV 1361: Ancient Viral Sword and Shield

Sep 27, 2026 · 1h 46m

Coming soon to iPhone. Already have it? “Listen in Starcast” takes you straight there.

On this episode

About this episode

TWiV explains discovery of a previously unknown mechanism of RNA-guided DNA recognition for genetic control that possibly predates the emergence of CRISPR pathways, and the possibility that Alzheimer’s Disease neuropathology evolved as a host defense response to microbial infection in the brain. Hosts: Vincent Racaniello, Alan Dove, and Brianne Barker Subscribe (free): Apple Podcasts, RSS, email Become a patron of TWiV! Links for this episode Support science education at MicrobeTV Bob Tesh dies (Galv News) Comment on propsed changes to NIH peer review (NIH) NIH peer review proposed changes (Forbes) Ancient RNA guided DNA recognition (Science) Noncontiguous geometric triplex (Science) p-tau…