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The a16z Show

The a16z Show

How to Build a Successful Company in an Era of Disruption

Aug 6, 2025 · 43m

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On this episode

About this episode

What happens when a startup becomes a giant—and then has to reinvent itself all over again? In this episode, Martin Casado sits down with Raghu Raghuram (former CEO of VMware) and Jeetu Patel (President and CPO at Cisco) for a deep, tactical conversation on scaling, disruption, and navigating transformation from the inside. They share hard-won lessons from leading two of the most iconic infrastructure companies in tech—through waves like virtualization, cloud, containers, and now AI. They cover: -How to keep innovation alive inside large companies -Why the best companies operate with a founder’s mindset, even without founders -The difference between selling to buyers vs. practitioners -Why…